Phenylethyl Anthranilate

Phenylethyl Anthranilate - Names and Identifiers

Name	Phenylethyl Anthranilate
Synonyms	Phenylethyl Anthranilate 2-phenylethyl-o-aminobenzoate 2-Phenylethyl 2-aminobenzoate 2-Phenylethyl o-aminobenzoate anthranilicacid,phenethylester Anthranilic acid, phenethyl ester 2-amino-benzoicaci2-phenylethylester Benzoicacid,2-amino-,2-phenylethylester Benzoic acid, 2-amino-, 2-phenylethyl ester
CAS	133-18-6
EINECS	205-098-0

Phenylethyl Anthranilate - Physico-chemical Properties

Molecular Formula	C15H15NO2
Molar Mass	241.29
Density	1.0944 (rough estimate)
Melting Point	39-44°C(lit.)
Boling Point	226°C(lit.)
FEMA	2859 \| PHENYLETHYL ANTHRANILATE
Flash Point	>230°F
JECFA Number	1543
Color	White to yellow crystals
Odor	grape odor
Refractive Index	1.5200 (estimate)
Physical and Chemical Properties	Colorless to light yellow crystals. Orange flower-like aroma and grape fragrance. Boiling point 324 °c. Soluble in ethanol.

Phenylethyl Anthranilate - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
UN IDs	UN 3077 9/PG 3
WGK Germany	2
RTECS	CB3720000
Toxicity	skn-rbt 500 mg/24H MOD FCTXAV 14,659,76

Phenylethyl Anthranilate - Introduction

Phenylethyl Anthranilate, also known as N-benzyl-N-phenylformamide or Benzocaine, is an organic compound. The following is a description of its nature, use, preparation and safety information:

1. Nature:
-Appearance: white crystalline powder or crystalline flake
-Solubility: Soluble in organic solvents, insoluble in water
-Melting Point: about 89-92 ℃
-molecular formula: C9H11NO2
-Molecular weight: 165.19g/mol

2. Use:
-Anesthetic: Phenylethyl Anthranilate is a local anesthetic commonly used to reduce pain and itching in the skin or mucous membranes. It is often used in the medical, dental, and cosmetic fields as a topical anesthetic or ingredient in oral preparations.
-Drug intermediate: It can also be used as a synthetic intermediate for certain drugs and used to prepare other drugs and compounds.
-Cosmetics: Due to its analgesic and anti-infection properties, Phenylethyl Anthranilate is also often used as an ingredient in cosmetics, such as mouth rinses, toothpastes, etc.

3. Preparation method:
Phenylethyl Anthranilate is usually prepared by reacting 2-amino-benzoic acid with 2-phenylethanol. Wherein, 2-amino-benzoic acid and 2-phenylethanol in the presence of a catalyst (such as sodium hydroxide), esterification reaction can be carried out to produce target product.

4. Safety Information:
- Phenylethyl Anthranilate is generally considered to be a relatively safe compound, but it is still necessary to follow safe procedures for use and storage.
-When exposed to Phenylethyl Anthranilate, take necessary personal protective measures, such as wearing protective gloves and goggles.
-Avoid inhaling powder or solution, and operate in a well-ventilated place.
-If ingested or inhaled, seek medical attention immediately and provide relevant chemical and safety information.

Last Update：2024-04-09 01:59:55